John P Atkinson Selected Research

Membrane Cofactor Protein

11/2020	CD46 and Oncologic Interactions: Friendly Fire against Cancer.
1/2008	Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome.
1/2007	Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome.
8/2006	Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.
7/2006	Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome.
10/2003	Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome.

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John P Atkinson Research Topics

Disease

19	Infections 01/2022 - 03/2002
15	Atypical Hemolytic Uremic Syndrome 07/2019 - 07/2006
11	Macular Degeneration (Age-Related Maculopathy) 01/2016 - 01/2007
8	Thrombotic Microangiopathies 01/2022 - 10/2003
7	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019 - 01/2003
5	Inflammation (Inflammations) 01/2021 - 05/2012
5	Thrombosis (Thrombus) 01/2019 - 12/2003
4	Neoplasms (Cancer) 10/2021 - 10/2004
4	Hemolytic-Uremic Syndrome 01/2008 - 10/2003
4	Protein Deficiency 01/2007 - 11/2005
3	COVID-19 02/2021 - 01/2020
3	Leukoencephalopathies 10/2020 - 11/2016
3	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2007
3	Arthritis (Polyarthritis) 01/2019 - 01/2010
3	Autoimmune Diseases (Autoimmune Disease) 01/2016 - 01/2010
3	Sepsis (Septicemia) 04/2014 - 12/2012
3	Vaccinia 09/2009 - 09/2005
3	Smallpox (Variola) 09/2009 - 03/2006
2	Thrombocytopenia (Thrombopenia) 01/2022 - 01/2019
2	Thrombophilia 02/2021 - 01/2020
2	Dengue (Dengue Fever) 01/2021 - 07/2011
2	Hemolysis 01/2019 - 01/2008
2	Rheumatoid Arthritis 01/2018 - 09/2010
2	Pre-Eclampsia (Preeclampsia) 01/2017 - 03/2011
2	Spontaneous Abortion (Miscarriage) 06/2013 - 03/2011
2	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 12/2012 - 06/2007
2	Abdominal Aortic Aneurysm 02/2012 - 04/2009
2	Malaria 01/2012 - 11/2002
2	Mpox (monkeypox) 09/2009 - 03/2006
2	HELLP Syndrome 11/2008 - 01/2008
1	Systemic Scleroderma (Systemic Sclerosis) 06/2022
1	Respiratory Insufficiency (Respiratory Failure) 02/2021
1	Human Influenza (Influenza) 02/2021
1	Critical Illness (Critically Ill) 02/2021
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2021
1	Ischemia 10/2020
1	Respiratory Sounds (Crackle) 01/2020
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2020
1	Cystic Fibrosis (Mucoviscidosis) 01/2020
1	Acute Lung Injury 01/2020
1	Reperfusion Injury 01/2020
1	Bronchiolitis 01/2020
1	Primary Graft Dysfunction 01/2020
1	Female Infertility 10/2019
1	Infertility (Sterility) 10/2019
1	Hematuria 01/2019
1	Exanthema (Rash) 01/2019
1	Obesity 01/2019
1	Lupus Nephritis 01/2019

Drug/Important Bio-Agent (IBA)

53	Complement System Proteins (Complement)IBA 01/2022 - 01/2003
11	Proteins (Proteins, Gene)FDA Link 10/2019 - 06/2005
8	Complement Factor H (Factor H)IBA 01/2016 - 10/2003
7	EnzymesIBA 01/2022 - 03/2006
6	Membrane Cofactor ProteinIBA 11/2020 - 10/2003
5	Retinaldehyde (Retinal)IBA 10/2020 - 06/2008
5	Fibrinogen (Factor I)FDA Link 07/2019 - 07/2006
4	Complement C3 (C3 Complement)IBA 10/2019 - 12/2008
4	chemotactic factor inactivatorIBA 07/2015 - 01/2008
3	RNA (Ribonucleic Acid)IBA 06/2022 - 04/2014
3	VaccinesIBA 01/2022 - 12/2010
3	LectinsIBA 01/2021 - 01/2011
3	Complement Inactivating AgentsIBA 01/2020 - 09/2009
3	CytokinesIBA 01/2020 - 12/2013
3	Complement Factor I (C3b Inactivator)IBA 07/2015 - 01/2008
3	AutoantibodiesIBA 12/2012 - 01/2003
3	AntibodiesIBA 11/2007 - 09/2003
2	von Willebrand FactorIBA 02/2021 - 01/2016
2	Pharmaceutical PreparationsIBA 02/2021 - 03/2002
2	Complement Factor D (Factor D)IBA 01/2019 - 01/2018
2	Antigen-Antibody Complex (Immune Complex)IBA 11/2018 - 01/2016
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 07/2015
2	DNA (Deoxyribonucleic Acid)IBA 10/2015 - 12/2009
2	Complement Factor B (Factor B)IBA 12/2013 - 09/2010
2	Glycoproteins (Glycoprotein)IBA 07/2013 - 11/2007
2	Complement C4b-Binding ProteinIBA 06/2013 - 07/2011
2	ProperdinIBA 02/2012 - 01/2010
2	Blood Group Antigens (Blood Groups)IBA 01/2012 - 11/2002
2	Membrane Proteins (Integral Membrane Proteins)IBA 03/2011 - 02/2004
2	Virulence Factors (Pathogenicity Factors)IBA 09/2008 - 03/2006
2	Granzymes (Granzyme)IBA 11/2004 - 10/2004
2	PerforinIBA 11/2004 - 10/2004
1	Threonine (L-Threonine)FDA Link 01/2022
1	Proline (L-Proline)FDA Link 01/2022
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	ThrombomodulinIBA 02/2021
1	Indicators and Reagents (Reagents)IBA 02/2021
1	Polysaccharides (Glycans)IBA 01/2021
1	Oxygen (Dioxygen)IBA 10/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	Monoclonal AntibodiesIBA 01/2020
1	Amyloid beta-PeptidesIBA 01/2020
1	Prostaglandins DIBA 01/2020
1	Biological ProductsIBA 10/2019
1	Sulfhydryl Compounds (Thiols)IBA 01/2019
1	LeptinIBA 01/2019
1	Diphtheria ToxinIBA 01/2019

Therapy/Procedure

4	Therapeutics 11/2020 - 12/2010
1	Artificial Respiration (Mechanical Ventilation) 02/2021
1	Lung Transplantation 01/2020